(Nasdaq: NGEN), (NASDAQ: ETFC), (PINKSHEETS: CWRM), (Pink Sheets: TCLT).

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Nanogen, Inc. (Nasdaq: NGEN)(February 1, 2008), developer of molecular and rapid diagnostic products, announced that the U.S. Patent and Trademark Office has granted two new patents; No. 7,319,022 titled "Amplification Methods" and No. 7,297,495 titled "Hybridization-Triggered Fluorescent Detection Of Nucleic Acids". The technologies described in these patents are important additions to the strong foundation of inventions in the Company's MGB Probe technology portfolio.

The Amplification Method invention describes the use of overlap primer/probe designs and specifically differentiates Nanogen primer and probe designs from conventional PCR techniques since the probe overlaps with a portion of the primer sequences. The overlap design allows the utilization of short, more conserved, primer and probe sequences which generate shorter amplicons and results in a more efficient PCR amplification reaction. "This patent is a key element of our real-time PCR product offering" stated Graham Lidgard, SVP of Research and Development for Nanogen. "The overlap design is an integral design element of the Company's MGB Alert(R) products that significantly differentiates these real-time PCR products in the market and adds performance and value for customers."

The second patent relates to the invention of a new fluorescent dye, cyanine dye, which simplifies PCR probe design requirements by eliminating the need for fluorescent quenchers. In classical real-time PCR, probes need a quencher molecule to keep the fluor from emitting signal in the non-hybridized state. This new cyanine dye, when used with the Company's MGB moiety, does not fluoresce when not hybridized, but it does fluoresce when hybridized to the target. This opens up new PCR probe design opportunities for the Company to use in its products or license to partners.

Nanogen now has more than 40 patents in the field of real-time PCR which play an important role in the Company's proprietary product offering and licensing programs. Nanogen's products are used by clinical laboratories to develop molecular diagnostic tests that will detect genetic sequences associated with pathogens including those often tested in immunocompromised patients such as cytomegalovirus, Epstein-Barr virus, and enterovirus.

Nanogen provides innovative, high quality diagnostic products to clinicians and physicians worldwide making it easier to predict, diagnose, and ultimately help treat diseases. The company's products include molecular diagnostic kits and reagents and kits for rapid, point-of-care testing. Nanogen has pioneered research in areas involving nanotechnology, biomarkers, and molecular biology to bring better results to diagnostics and healthcare.

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Cotton & Western Mining, Inc. (PINKSHEETS: CWRM)(February 1, 2008), Robert L. Cotton, President & C.E.O. of Houston-based Cotton & Western Mining, said today that the company is expecting to get at minimum six months production from its Baja California new iron and copper ore production in year 2008 and with metal mineral prices at all time highs, only 60,000 dry metric tons of copper ore and 900,000 dry metric tons of iron ores would be needed to exceed $100,000,000.00 in gross revenues.

The company anticipates production of crude iron and crude copper ore to begin no later than June, 2008 with modest expectations for production of ores.

The company has received several offers within the last few weeks for off-take agreements for both the iron ore and copper ore production from its Baja Pacific No. 5 mineral deposit. Bench mark pricing for the first quarter of 2008 for raw crude iron ore in fines at minimum 64.5% Fe is $62.00 F.O.B. per each dry metric ton and bench mark pricing for the first quarter of 2008 for raw crude copper ore in lump at minimum 28% Cu is $1,350.00 C.I.F. per each dry metric ton. The company is planning on setting up production of copper ore at 10,000 DMT per month and production for iron ore fines will be set at 150,000 DMT per month.

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Techalt, Inc. (Pink Sheets:TCLT) (February 1, 2008) updates its shareholders and the investment community that its signed merger agreement with EV Parts, Inc. ("EV Parts"), a leading online supplier of electric vehicle parts and components, which the Company previously announced it expected to close on or before March 18, 2008, is now anticipated to close the first week in February 2008.

David Moore President of Techalt stated, "We have been very busy trying to meet the conditions necessary to close the merger agreement with EV Parts and I am extremely pleased that it looks like the merger will close much earlier than initially expected."

The Company also wishes to announce that due diligence review of the company holding the licensing rights to the cream best known for treating and preventing open wounds to the skin often incurred through athletic activities is complete and final contracts to acquire the licensing rights to the cream are in legal review.

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